TITANIUM DIOXIDE NANOPARTICLES: OCCUPATIONAL EXPOSURE LIMITS

[Titanium dioxide nanoparticles: occupational exposure limits].

Titanium dioxide (TiO2) is produced in Poland as a high production volume chemical (HPVC). It is used mainly as a pigment for paints and coatings, plastics, paper, and also as additives to food and pharmaceuticals. Titanium dioxide nanoparticles are increasingly applied in cosmetics, textiles and plastics as the ultraviolet light blocker. This contributes to a growing occupational exposure to T...

Oral toxic exposure of titanium dioxide nanoparticles on serum biochemical changes in adult male Wistar rats

Objective(s): Titanium dioxide (TiO2) nanoparticles (NPs) are widely used in commercial food additives and cosmetics worldwide. Uptake of these nanoparticulate into humans by different routes and may exhibit potential side effects, lags behind the rapid development of nanotechnology. Thus, the present study designed to evaluate the toxic effect of mixed rutile and anatase TiO2 NPs on serum bioc...

Titanium Dioxide Nanoparticles: Grassian et al. Respond

Aggregation and Toxicology of Titanium Dioxide Nanoparticles

In their study of inhalation exposure of titanium dioxide particles, Grassian et al. (2007) presented a transmission electron micrograph (TEM) (their Figure 2A) as an image of “dispersed” TiO2 nanoparticles. Yet, the TiO2 nanoparticles in this TEM do not appear to be dispersed. There is clear evidence of self-organization of the nanoparticles into distinct assemblages, separated by relatively l...

Mucin Secretion Induced by Titanium Dioxide Nanoparticles

Nanoparticle (NP) exposure has been closely associated with the exacerbation and pathophysiology of many respiratory diseases such as Chronic Obstructive Pulmonary Disease (COPD) and asthma. Mucus hypersecretion and accumulation in the airway are major clinical manifestations commonly found in these diseases. Among a broad spectrum of NPs, titanium dioxide (TiO(2)), one of the PM10 components, ...